Agent Nateur
Duo Holi ( Mane) + Holi (Radiance)

Collagen makes up 70% of your dermis (the middle layer of your skin) and high collagen levels in the body prevent bone loss and joint regeneration. It also promotes excellent hair, skin, and nail health. 
As we age, our collagen levels naturally start to decline, so supplementing with high-quality collagen can prevent noticeable signs of aging. An eight-week study showed that daily collagen supplements significantly improved skin moisture and skin elasticity both during and after the trial.
Meanwhile, MSM is a stable sulfur compound that is often called a ‘mineral of beauty.' Studies confirm MSM’s ability to improve human skin hydration and elasticity. MSM also acts as a sulfur donor to keratin, a protein that plays an important role and strengthens hair growth, hair regeneration, and overall hair health.  
To that end, MSM is an anti-inflammatory and antioxidant. The anti-inflammatory properties of MSM are well documented by scientific research. The wonder ingredient has been proven to effectively fight against reactive oxygen species and free radicals in the body that impact our skin health at a cellular level. MSM is also a precursor to glutathione, helping our body to detoxify and fight against candida overgrowth and help with joint pain, inflammatory pain conditions, and chronic pain. 
Ceramosides are the second ingredient in our new holi (radiance) formula.  Dr. Will Cole suggested adding ceramosides because they are a lipid found naturally in the skin and support the skin’s structure and function. As we age, we lose ceramosides, our moisture barrier gets impacted, and there are changes in skin texture such as sagging, fine lines, and wrinkles. Taking ceramosides orally brings new ceramides to the skin via the bloodstream and helps restore the water barrier, stopping trans-epidermal water loss, replenishing cracks in the skin, helping hydration and plumpness, and stopping skin degradation, all while moisturizing the skin for a healthy glow.

Combining MSM and collagen is an exciting next step when it comes to beauty from within. By blending collagen peptides with MSM, the combination accelerates the process of setting off fibroblasts in the skin. This means that the body produces new collagen even faster and the state of skin will improve quicker than taking either on its own. 
The clinicals on MSM and collagen pairing was completed as a randomized, double-blind, placebo-controlled study involving 27 women between the age of 40 and 65 with a BMI lower than 35. Over the course of 12 weeks, the study looked at how the combination of MSM and collagen could promote the synthesis of collagen and elastin fibers in the dermal layer of the skin. The clinical study showed significant improvements in skin health. Here are the findings: 
• A 19% improvement in dermis density using a collagen and MSM combination. This was compared to no change in dermis density for the placebo group.
• A 40% increase in skin hydration and a 12% reduction in skin roughness. The addition of MSM to the trial also doubled the reduction of skin roughness compared to collagen supplementation alone. 
• A 12% difference in skin texture using collagen and MSM compared to higher concentrated supplement that only contained collagen.
• A reduction in wrinkles by 21% and reduction in wrinkle volume by 15%. It confirmed that wrinkles appear as a consequence of thinner, and less hydrated skin. The combination of MSM and collagen worked to reverse this.